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Caffeine inhibits glucose transport by binding at the GLUT1 nucleotide-binding site

Glucose transporter 1 (GLUT1) is the primary glucose transport protein of the cardiovascular system and astroglia. A recent study proposes that caffeine uncompetitive inhibition of GLUT1 results from interactions at an exofacial GLUT1 site. Intracellular ATP is also an uncompetitive GLUT1 inhibitor...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Sage, Jay M., Cura, Anthony J., Lloyd, Kenneth P., Carruthers, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436993/
https://ncbi.nlm.nih.gov/pubmed/25715702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2015
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