WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site

WZB117 (2-fluoro-6-(m-hydroxybenzoyloxy) phenyl m-hydroxybenzoate) inhibits passive sugar transport in human erythrocytes and cancer cell lines and, by limiting glycolysis, inhibits tumor growth in mice. This study explores how WZB117 inhibits the erythrocyte sugar transporter glucose transport prot...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Ojelabi, Ogooluwa A., Lloyd, Kenneth P., Simon, Andrew H., De Zutter, Julie K., Carruthers, Anthony
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Membrane Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207184/
https://ncbi.nlm.nih.gov/pubmed/27836974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759175
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