K63-linked ubiquitylation induces global sequestration of mitochondria

Even though K63-linked polyubiquitin chains do not target proteins for proteasomal degradation, they play nevertheless a complementary protective role in maintaining protein homeostasis by directing malfunctioning proteins and organelles to inclusion bodies or autophagosomes. A paradigm for this pro...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Richard, Thibaud J. C., Herzog, Laura K., Vornberger, Julia, Rahmanto, Aldwin Suryo, Sangfelt, Olle, Salomons, Florian A., Dantuma, Nico P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749161/
https://ncbi.nlm.nih.gov/pubmed/33339882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78845-7
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