Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase

RNA synthesis is central to life, and RNA polymerase (RNAP) depends on accessory factors for recovery from stalled states and adaptation to environmental changes. Here, we investigated the mechanism by which a helicase-like factor HelD recycles RNAP. We report a cryo-EM structure of a complex betwee...

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Publicado no:Nat Commun
Main Authors: Kouba, Tomáš, Koval’, Tomáš, Sudzinová, Petra, Pospíšil, Jiří, Brezovská, Barbora, Hnilicová, Jarmila, Šanderová, Hana, Janoušková, Martina, Šiková, Michaela, Halada, Petr, Sýkora, Michal, Barvík, Ivan, Nováček, Jiří, Trundová, Mária, Dušková, Jarmila, Skálová, Tereza, Chon, URee, Murakami, Katsuhiko S., Dohnálek, Jan, Krásný, Libor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749160/
https://ncbi.nlm.nih.gov/pubmed/33339823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20158-4
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