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The Core and Holoenzyme Forms of RNA Polymerase from Mycobacterium smegmatis

Bacterial RNA polymerase (RNAP) is essential for gene expression and as such is a valid drug target. Hence, it is imperative to know its structure and dynamics. Here, we present two as-yet-unreported forms of Mycobacterium smegmatis RNAP: core and holoenzyme containing σ(A) but no other factors. Eac...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Kouba, Tomáš, Pospíšil, Jiří, Hnilicová, Jarmila, Šanderová, Hana, Barvík, Ivan, Krásný, Libor
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351736/
https://ncbi.nlm.nih.gov/pubmed/30478083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00583-18
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