The torpedo effect in Bacillus subtilis: RNase J1 resolves stalled transcription complexes

RNase J1 is the major 5′‐to‐3′ bacterial exoribonuclease. We demonstrate that in its absence, RNA polymerases (RNAPs) are redistributed on DNA, with increased RNAP occupancy on some genes without a parallel increase in transcriptional output. This suggests that some of these RNAPs represent stalled,...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Šiková, Michaela, Wiedermannová, Jana, Převorovský, Martin, Barvík, Ivan, Sudzinová, Petra, Kofroňová, Olga, Benada, Oldřich, Šanderová, Hana, Condon, Ciarán, Krásný, Libor
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996504/
https://ncbi.nlm.nih.gov/pubmed/31840842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102500
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