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The torpedo effect in Bacillus subtilis: RNase J1 resolves stalled transcription complexes
RNase J1 is the major 5′‐to‐3′ bacterial exoribonuclease. We demonstrate that in its absence, RNA polymerases (RNAPs) are redistributed on DNA, with increased RNAP occupancy on some genes without a parallel increase in transcriptional output. This suggests that some of these RNAPs represent stalled,...
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| 發表在: | EMBO J |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996504/ https://ncbi.nlm.nih.gov/pubmed/31840842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102500 |
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