The torpedo effect in Bacillus subtilis: RNase J1 resolves stalled transcription complexes

RNase J1 is the major 5′‐to‐3′ bacterial exoribonuclease. We demonstrate that in its absence, RNA polymerases (RNAPs) are redistributed on DNA, with increased RNAP occupancy on some genes without a parallel increase in transcriptional output. This suggests that some of these RNAPs represent stalled,...

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Publicat a:EMBO J
Autors principals: Šiková, Michaela, Wiedermannová, Jana, Převorovský, Martin, Barvík, Ivan, Sudzinová, Petra, Kofroňová, Olga, Benada, Oldřich, Šanderová, Hana, Condon, Ciarán, Krásný, Libor
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996504/
https://ncbi.nlm.nih.gov/pubmed/31840842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102500
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