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Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases
Oxytosis was first described over 30 years ago in nerve cells as a non-excitotoxic pathway for glutamate-induced cell death. The key steps of oxytosis, including glutathione depletion, lipoxygenase activation, reactive oxygen species accumulation and calcium influx, were identified using a combinati...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749085/ https://ncbi.nlm.nih.gov/pubmed/33176157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.10.010 |
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