Transcriptomic signatures of oxytosis/ferroptosis are enriched in Alzheimer’s disease

Abstract Background Oxytosis/ferroptosis is a form of non-apoptotic regulated cell death characterized by specific changes in the redox balance that lead to lethal lipid peroxidation. It has been hypothesized recently that aging predisposes the brain to the activation of oxytosis/ferroptosis in Alzh...

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Hlavní autoři:	Antonio Currais, Kayla Sanchez, David Soriano-Castell, Nawab John Dar, K. Garrett Evensen, Salvador Soriano, Pamela Maher
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	BMC Biology
Témata:	Oxytosis/ferroptosis Alzheimer’s disease Transcriptomics Integrated stress response (ISR) Activating transcription factor 4 (ATF4)
On-line přístup:	https://doi.org/10.1186/s12915-025-02235-6
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