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Metabolic Coordination of Cell Fate by α-Ketoglutarate-Dependent Dioxygenases

Cell fate determination requires faithful execution of gene expression programs, which are increasingly recognized to respond to metabolic inputs. In particular, the family of α-ketoglutarate (αKG)-dependent dioxygenases, which include several chromatin-modifying enzymes, are emerging as key mediato...

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Veröffentlicht in:Trends Cell Biol
Hauptverfasser: Baksh, Sanjeethan C., Finley, Lydia W.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748998/
https://ncbi.nlm.nih.gov/pubmed/33092942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2020.09.010
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