FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression

Ferredoxin reductase (FDXR) is a mitochondrial flavoprotein that initiates electron transport from NADPH to several cytochromes P450 via two electron carriers, ferredoxin 1 (FDX1) and FDX2. FDXR is the sole ferredoxin reductase in humans and plays a critical role in steroidogenesis and biosynthesis...

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Pubblicato in:J Pathol
Autori principali: Zhang, Jin, Kong, Xiangmudong, Zhang, Yanhong, Sun, Wenqiang, Wang, Jian, Chen, Mingyi, Chen, Xinbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748393/
https://ncbi.nlm.nih.gov/pubmed/32304229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5451
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