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ATM inhibition enhances Auranofin-induced oxidative stress and cell death in lung cell lines
Ataxia-Telangiectasia (A-T), a pleiotropic chromosomal breakage syndrome, is caused by the loss of the kinase Ataxia-telangiectasia mutated (ATM). ATM is not only involved in the response to DNA damage, but also in sensing and counteracting oxidative stress. Since a disturbed redox balance has been...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7748142/ https://ncbi.nlm.nih.gov/pubmed/33338048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244060 |
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