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Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death

Recent genomic studies revealed a high rate of recurrent mutations in the RAS pathway in primary rhabdomyosarcoma (RMS) samples. In the present study, we therefore investigated how oncogenic RAS mutants impinge on the regulation of cell death of RMS13 cells. Here, we report that ectopic expression o...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Schott, Christina, Graab, Ulrike, Cuvelier, Nicole, Hahn, Heidi, Fulda, Simone
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476278/
https://ncbi.nlm.nih.gov/pubmed/26157704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00131
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