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ATM inhibition enhances Auranofin-induced oxidative stress and cell death in lung cell lines

Ataxia-Telangiectasia (A-T), a pleiotropic chromosomal breakage syndrome, is caused by the loss of the kinase Ataxia-telangiectasia mutated (ATM). ATM is not only involved in the response to DNA damage, but also in sensing and counteracting oxidative stress. Since a disturbed redox balance has been...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Ehrenfeld, Vanessa, Heusel, Jan R., Fulda, Simone, van Wijk, Sjoerd J. L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748142/
https://ncbi.nlm.nih.gov/pubmed/33338048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244060
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