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Quantile-specific heritability of sibling leptin concentrations and its implications for gene-environment interactions

“Quantile-dependent expressivity” occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g., leptin) is high or low relative to its distribution. Leptin concentrations are strongly related to adiposity, whose heritability is quantile dependent. Whether inheritance of...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile nagusia: Williams, Paul T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747738/
https://ncbi.nlm.nih.gov/pubmed/33335207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79116-1
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