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pH-controlled stacking direction of the β-strands in peptide fibrils

Peptides provide a framework for generating functional biopolymers. In this study, the pH-dependent structural changes in the 21–29 fragment peptide of β(2)-microglobulin (β(2)m(21–29)) during self-aggregation, i.e., the formation of an amyloid fibril, were discussed. The β-sheet structures formed d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tseng, Wei-Hsuan, Chen, Szu-Hua, Hiramatsu, Hirotsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747703/
https://ncbi.nlm.nih.gov/pubmed/33335192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79001-x
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