Inhibition of Glycogen Synthase Kinase 3β Increases the Proportion and Suppressive Function of CD19(+)CD24(hi)CD27(+) Breg Cells

CD19(+)CD24(hi)CD27(+) memory Breg cells exhibit decreased abundance in patients with chronic graft-versus-host disease (cGVHD) after liver transplantation and produce less IL-10 than those from patients without cGVHD and healthy donors. Due to the lack of Breg cells and the difficulty in expanding...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Li, Jinyang, Gao, Ji, Zhou, Haoming, Zhou, Jinren, Deng, Zhenghua, Lu, Yunjie, Rao, Jianhua, Ji, Guwei, Gu, Jian, Yang, Xinxiang, Xia, Yongxiang, Wang, Xuehao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746849/
https://ncbi.nlm.nih.gov/pubmed/33343576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.603288
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