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Decrease in Proportion of CD19(+)CD24(hi)CD27(+) B Cells and Impairment of Their Suppressive Function in Graves’ Disease

IL-10-producing B cells (B10 cells) have been shown to play a suppressive role in the peripheral blood of humans, with their numbers and function altered in several autoimmune diseases. However, the role of B10 cells in Graves’ disease (GD) remains unknown. In this study, we demonstrated that B10 ce...

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Detalhes bibliográficos
Main Authors: Zha, Bingbing, Wang, Luman, Liu, Xiaoming, Liu, Jun, Chen, Zaoping, Xu, Jiong, Sheng, Li, Li, Yiming, Chu, Yiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506658/
https://ncbi.nlm.nih.gov/pubmed/23189166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049835
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