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Structure, membrane topology and influence of cholesterol of the membrane proximal region: transmembrane helical anchor sequence of gp41 from HIV

During the first steps of HIV infection the Env subunit gp41 is thought to establish contact between the membranes and to be the main driver of fusion. Here we investigated in liquid crystalline membranes the structure and cholesterol recognition of constructs made of a gp41 external region carrying...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Aisenbrey, Christopher, Rifi, Omar, Bechinger, Burkhard
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746737/
https://ncbi.nlm.nih.gov/pubmed/33335248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79327-6
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