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IL4I1 Accelerates the Expansion of Effector CD8(+) T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell Activation
IL4I1 is an immunoregulatory enzyme that inhibits CD8 T-cell proliferation in vitro and in the tumoral context. Here, we dissected the effect of IL4I1 on CD8 T-cell priming by studying the differentiation of a transgenic CD8 T-cell clone and the endogenous repertoire in a mouse model of acute lympho...
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| Publicat a: | Front Immunol |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7746639/ https://ncbi.nlm.nih.gov/pubmed/33343572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.600012 |
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