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Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
TRPV3 is a temperature-sensitive, nonselective cation channel expressed prominently in skin keratinocytes. TRPV3 plays important roles in hair morphogenesis and maintenance of epidermal barrier function. Gain-of-function mutations of TRPV3 have been found in both humans and rodents and are associate...
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| Publié dans: | J Gen Physiol |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745752/ https://ncbi.nlm.nih.gov/pubmed/33320167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012663 |
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