Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors

Epigenetic mechanisms are involved in epilepsy and chronic pain development. About that, we studied the effects of the natural histone deacetylase (HDAC) inhibitor sodium butyrate (BUT) in comparison with valproic acid (VPA) in a validated genetic model of generalized absence epilepsy and epileptoge...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: De Caro, Carmen, Di Cesare Mannelli, Lorenzo, Branca, Jacopo Junio Valerio, Micheli, Laura, Citraro, Rita, Russo, Emilio, De Sarro, Giovambattista, Ghelardini, Carla, Calignano, Antonio, Russo, Roberto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7745735/
https://ncbi.nlm.nih.gov/pubmed/33343343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.549191
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