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IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy

Increased expression of interleukin-6 (IL-6) both in cerebrospinal fluid (CSF) and plasma is closely associated with convulsive epilepsy and symptom severity of depression. By comparison, at present, little is known about the role of this cytokine in childhood (non-convulsive) absence epilepsy. The...

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發表在:Neurotherapeutics
Main Authors: Leo, Antonio, Nesci, Valentina, Tallarico, Martina, Amodio, Nicola, Gallo Cantafio, Eugenia M., De Sarro, Giovambattista, Constanti, Andrew, Russo, Emilio, Citraro, Rita
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851197/
https://ncbi.nlm.nih.gov/pubmed/32681356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00893-8
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