IL-6 Receptor Blockade by Tocilizumab Has Anti-absence and Anti-epileptogenic Effects in the WAG/Rij Rat Model of Absence Epilepsy

Increased expression of interleukin-6 (IL-6) both in cerebrospinal fluid (CSF) and plasma is closely associated with convulsive epilepsy and symptom severity of depression. By comparison, at present, little is known about the role of this cytokine in childhood (non-convulsive) absence epilepsy. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurotherapeutics
Prif Awduron: Leo, Antonio, Nesci, Valentina, Tallarico, Martina, Amodio, Nicola, Gallo Cantafio, Eugenia M., De Sarro, Giovambattista, Constanti, Andrew, Russo, Emilio, Citraro, Rita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2020
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851197/
https://ncbi.nlm.nih.gov/pubmed/32681356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-020-00893-8
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