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Syk facilitates phagosome-lysosome fusion by regulating actin-remodeling in complement-mediated phagocytosis
Effective phagocytosis is crucial for host defense against pathogens. Macrophages entrap pathogens into a phagosome and subsequently acidic lysosomes fuse to the phagosome. Previous studies showed the pivotal role of actin-remodeling mediated by phosphoinositide-related signaling in phagosome format...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7744523/ https://ncbi.nlm.nih.gov/pubmed/33328565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79156-7 |
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