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Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase

Dysfunction in mitochondrial dynamics is believed to contribute to a host of neurological disorders and has recently been implicated in cancer metastasis. The outer mitochondrial membrane adapter protein Miro functions in the regulation of mitochondrial mobility and degradation, however, the structu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Struct Biol
Hauptverfasser: Smith, Kyle P., Focia, Pamela J., Chakravarthy, Srinivas, Landahl, Eric C., Klosowiak, Julian L., Rice, Sarah E., Freymann, Douglas M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744357/
https://ncbi.nlm.nih.gov/pubmed/33132189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2020.107656
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