Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro

Miro is a highly conserved calcium-binding GTPase at the regulatory nexus of mitochondrial transport and autophagy. Here we present crystal structures comprising the tandem EF hand and carboxy terminal GTPase (cGTPase) domains of Drosophila Miro. The structures reveal two previously unidentified ‘hi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Klosowiak, Julian L, Focia, Pamela J, Chakravarthy, Srinivas, Landahl, Eric C, Freymann, Douglas M, Rice, Sarah E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: European Molecular Biology Organization 2013
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818075/
https://ncbi.nlm.nih.gov/pubmed/24071720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.151
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