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Pro-inflammatory CD8 T Cells Contribute to Age-Related Large Artery Stiffening

We have shown that T cells accumulate around the aorta with advanced age and that both pharmacologic and genetic deletion of total T cells result in improved large artery stiffness in old mice. The purpose of this study was to test the hypothesis that CD8 T cells specifically mediate age-related lar...

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Dettagli Bibliografici
Pubblicato in:Innov Aging
Autori principali: Trott, Daniel, Sharma, Sunita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741224/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.440
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