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Pro-inflammatory CD8 T Cells Contribute to Age-Related Large Artery Stiffening

We have shown that T cells accumulate around the aorta with advanced age and that both pharmacologic and genetic deletion of total T cells result in improved large artery stiffness in old mice. The purpose of this study was to test the hypothesis that CD8 T cells specifically mediate age-related lar...

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Bibliografski detalji
Izdano u:Innov Aging
Glavni autori: Trott, Daniel, Sharma, Sunita
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741224/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.440
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