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A phenotypic switch in the dispersal strategy of breast cancer cells selected for metastatic colonization

An important question in cancer evolution concerns which traits make a cell likely to successfully metastasize. Cell motility phenotypes, mediated by cell shape change, are strong candidates. We experimentally evolved breast cancer cells in vitro for metastatic capability, using selective regimes de...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Butler, George, Keeton, Shirley J., Johnson, Louise J., Dash, Philip R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739941/
https://ncbi.nlm.nih.gov/pubmed/33259764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2020.2523
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