Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization

The two major isoforms of the paired-related homeodomain transcription factor 1 (Prrx1), Prrx1a and Prrx1b, are involved in pancreatic development, pancreatitis, and carcinogenesis, although the biological role that these isoforms serve in the systemic dissemination of pancreatic ductal adenocarcino...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Takano, Shigetsugu, Reichert, Maximilian, Bakir, Basil, Das, Koushik K., Nishida, Takahiro, Miyazaki, Masaru, Heeg, Steffen, Collins, Meredith A., Marchand, Benoît, Hicks, Philip D., Maitra, Anirban, Rustgi, Anil K.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719312/
https://ncbi.nlm.nih.gov/pubmed/26773005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263327.115
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