The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis

Pancreatic exocrine cell plasticity can be observed during development, pancreatitis with subsequent regeneration, and also transformation. For example, acinar–ductal metaplasia (ADM) occurs during acute pancreatitis and might be viewed as a prelude to pancreatic intraepithelial neoplasia (PanIN) an...

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Autori principali: Reichert, Maximilian, Takano, Shigetsugu, von Burstin, Johannes, Kim, Sang-Bae, Lee, Ju-Seog, Ihida-Stansbury, Kaori, Hahn, Christopher, Heeg, Steffen, Schneider, Günter, Rhim, Andrew D., Stanger, Ben Z., Rustgi, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576514/
https://ncbi.nlm.nih.gov/pubmed/23355395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.204453.112
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