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Optogenetically-induced long term depression in the rat orbitofrontal cortex ameliorates stress-induced reversal learning impairment

Cognitive flexibility is a higher-order executive function that requires plasticity in neuronal circuits of the prefrontal cortex. Deficits in cognitive flexibility are prominent in a variety of psychiatric disorders, such as major depression, obsessive-compulsive disorder, and posttraumatic stress...

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Detalhes bibliográficos
Publicado no:Neurobiol Stress
Main Authors: Adler, Samantha M., Girotti, Milena, Morilak, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739068/
https://ncbi.nlm.nih.gov/pubmed/33344713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynstr.2020.100258
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