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Encoding Changes in Orbitofrontal Cortex in Reversal-Impaired Aged Rats
Previous work in rats and primates has shown that normal aging can be associated with a decline in cognitive flexibility mediated by prefrontal circuits. For example, aged rats are impaired in rapid reversal learning, which in young rats depends critically on the orbitofrontal cortex. To assess whet...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430623/ https://ncbi.nlm.nih.gov/pubmed/16338994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01052.2005 |
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