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Encoding Changes in Orbitofrontal Cortex in Reversal-Impaired Aged Rats

Previous work in rats and primates has shown that normal aging can be associated with a decline in cognitive flexibility mediated by prefrontal circuits. For example, aged rats are impaired in rapid reversal learning, which in young rats depends critically on the orbitofrontal cortex. To assess whet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schoenbaum, Geoffrey, Setlow, Barry, Saddoris, Michael P., Gallagher, Michela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430623/
https://ncbi.nlm.nih.gov/pubmed/16338994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01052.2005
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