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Encoding Changes in Orbitofrontal Cortex in Reversal-Impaired Aged Rats

Previous work in rats and primates has shown that normal aging can be associated with a decline in cognitive flexibility mediated by prefrontal circuits. For example, aged rats are impaired in rapid reversal learning, which in young rats depends critically on the orbitofrontal cortex. To assess whet...

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書誌詳細
主要な著者: Schoenbaum, Geoffrey, Setlow, Barry, Saddoris, Michael P., Gallagher, Michela
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430623/
https://ncbi.nlm.nih.gov/pubmed/16338994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01052.2005
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