Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway

Background: Triple-negative breast cancer (TNBC) is a great threat to global women's health due to its high metastatic potential. Epithelial-to-mesenchymal transition (EMT) is considered as a key event in the process of metastasis. So the pharmacological targeting of EMT might be a promising st...

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Publicat a:J Cancer
Autors principals: Bao, Chang, Liu, Tao, Qian, Lingbo, Xiao, Chi, Zhou, Xinru, Ai, Heng, Wang, Jue, Fan, Weimin, Pan, Jie
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7738816/
https://ncbi.nlm.nih.gov/pubmed/33391404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.47553
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