MicroRNA-21 activation of Akt via PTEN is involved in the epithelial–mesenchymal transition and malignant transformation of human keratinocytes induced by arsenite

MicroRNAs are involved in the epithelial–mesenchymal transition (EMT) and malignant transformation of cells. However, the molecular mechanisms remain unclear. In seeking new biomarkers of chemical exposure in the risk assessment of arsenite-induced skin cancer, the function of microRNA-21 (miR-21) i...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Lu, Xiaolin, Liu, Yang, Luo, Fei, Zhang, Aihua, Liu, Xinlu, Lu, Lu, Shi, Le, Li, Jun, Xue, Junchao, Xu, Hui, Fan, Weimin, Liu, Qizhan
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062343/
https://ncbi.nlm.nih.gov/pubmed/30090420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00041j
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