MicroRNA-21 activation of Akt via PTEN is involved in the epithelial–mesenchymal transition and malignant transformation of human keratinocytes induced by arsenite

MicroRNAs are involved in the epithelial–mesenchymal transition (EMT) and malignant transformation of cells. However, the molecular mechanisms remain unclear. In seeking new biomarkers of chemical exposure in the risk assessment of arsenite-induced skin cancer, the function of microRNA-21 (miR-21) i...

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Vydáno v:Toxicol Res (Camb)
Hlavní autoři: Lu, Xiaolin, Liu, Yang, Luo, Fei, Zhang, Aihua, Liu, Xinlu, Lu, Lu, Shi, Le, Li, Jun, Xue, Junchao, Xu, Hui, Fan, Weimin, Liu, Qizhan
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062343/
https://ncbi.nlm.nih.gov/pubmed/30090420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6tx00041j
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