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MiR-21-5p Links Epithelial-Mesenchymal Transition Phenotype with Stem-Like Cell Signatures via AKT Signaling in Keloid Keratinocytes

Keloid is the abnormal wound healing puzzled by the aggressive growth and high recurrence rate due to its unrevealed key pathogenic mechanism. MicroRNAs contribute to a series of biological processes including epithelial-mesenchymal transition (EMT) and cells stemness involved in fibrotic disease. H...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Yan, Li, Cao, Rui, Liu, YuanBo, Wang, LianZhao, Pan, Bo, Lv, XiaoYan, Jiao, Hu, Zhuang, Qiang, Sun, XueJian, Xiao, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011940/
https://ncbi.nlm.nih.gov/pubmed/27596120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28281
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