In Vitro Profiling of Laninamivir-Resistant Substitutions in N3 to N9 Avian Influenza Virus Neuraminidase Subtypes and Their Association with In Vivo Susceptibility

Laninamivir (LAN) is a long-acting neuraminidase (NA) inhibitor (NAI) with a similar binding profile in the influenza NA enzyme active site as those of other NAIs, oseltamivir (OS), zanamivir (ZAN), and peramivir, and may share common resistance markers with these NAIs. We screened viruses with NA s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Jeong, Ju Hwan, Choi, Won-Suk, Antigua, Khristine Joy C., Choi, Young Ki, Govorkova, Elena A., Webby, Richard J., Baek, Yun Hee, Song, Min-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737746/
https://ncbi.nlm.nih.gov/pubmed/33055248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01679-20
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