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In Vitro and In Vivo Characterization of Novel Neuraminidase Substitutions in Influenza A(H1N1)pdm09 Virus Identified Using Laninamivir-Mediated In Vitro Selection

Neuraminidase (NA) inhibitors (NAIs) are widely used antiviral drugs for the treatment of humans with influenza virus infections. There have been widespread reports of NAI resistance among seasonal A(H1N1) viruses, and most have been identified in oseltamivir-exposed patients or those treated with o...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Lloren, Khristine Kaith S., Kwon, Jin Jung, Choi, Won-Suk, Jeong, Ju Hwan, Ahn, Su Jeong, Choi, Young Ki, Baek, Yun Hee, Song, Min-Suk
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401420/
https://ncbi.nlm.nih.gov/pubmed/30602610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01825-18
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