In Vitro and In Vivo Characterization of Novel Neuraminidase Substitutions in Influenza A(H1N1)pdm09 Virus Identified Using Laninamivir-Mediated In Vitro Selection

Neuraminidase (NA) inhibitors (NAIs) are widely used antiviral drugs for the treatment of humans with influenza virus infections. There have been widespread reports of NAI resistance among seasonal A(H1N1) viruses, and most have been identified in oseltamivir-exposed patients or those treated with o...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Lloren, Khristine Kaith S., Kwon, Jin Jung, Choi, Won-Suk, Jeong, Ju Hwan, Ahn, Su Jeong, Choi, Young Ki, Baek, Yun Hee, Song, Min-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401420/
https://ncbi.nlm.nih.gov/pubmed/30602610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01825-18
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