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Intrapulmonary Pharmacokinetics of Laninamivir, a Neuraminidase Inhibitor, after a Single Nebulized Administration of Laninamivir Octanoate in Healthy Japanese Subjects

A single dose of laninamivir octanoate (LO) inhaled using a dry powder inhaler (DPI) is effective for the treatment and prophylaxis of influenza. Nebulizers are an option for pediatric and elderly patients who may have difficulty in using a DPI. A single-center, open-label study was conducted to eva...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Toyama, Kaoru, Furuie, Hidetoshi, Ishizuka, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740362/
https://ncbi.nlm.nih.gov/pubmed/29061751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01722-17
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