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Intrapulmonary Pharmacokinetics of S-013420, a Novel Bicyclolide Antibacterial, in Healthy Japanese Subjects

S-013420 (EDP-420) is a novel bicyclolide (bridged bicyclic macrolide) antibacterial currently under development for the treatment of respiratory tract infections. The objective of the present study was to determine the plasma and intrapulmonary pharmacokinetic parameters of orally administered S-01...

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Bibliografiske detaljer
Main Authors: Furuie, Hidetoshi, Saisho, Yutaka, Yoshikawa, Takayoshi, Shimada, Jingoro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812166/
https://ncbi.nlm.nih.gov/pubmed/19933801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00567-09
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