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Intrapulmonary Pharmacokinetics of S-013420, a Novel Bicyclolide Antibacterial, in Healthy Japanese Subjects

S-013420 (EDP-420) is a novel bicyclolide (bridged bicyclic macrolide) antibacterial currently under development for the treatment of respiratory tract infections. The objective of the present study was to determine the plasma and intrapulmonary pharmacokinetic parameters of orally administered S-01...

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Detalhes bibliográficos
Main Authors: Furuie, Hidetoshi, Saisho, Yutaka, Yoshikawa, Takayoshi, Shimada, Jingoro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812166/
https://ncbi.nlm.nih.gov/pubmed/19933801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00567-09
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