High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing

Norovirus (NoV) infections are a leading cause of gastroenteritis. The humoral immune response plays an important role in the control of NoV, and recent studies have identified neutralizing antibodies that bind the capsid protein VP1 to block viral infection. Here, we utilize a NoV GI.1 Jun-Fos-assi...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Huang, Wanzhi, Soeung, Victoria, Boragine, David M., Hu, Liya, Prasad, B. V. Venkataram, Estes, Mary K., Atmar, Robert L., Palzkill, Timothy
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737742/
https://ncbi.nlm.nih.gov/pubmed/33055250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01495-20
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