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Development of a Gaussia Luciferase-Based Human Norovirus Protease Reporter System: Cell Type-Specific Profile of Norwalk Virus Protease Precursors and Evaluation of Inhibitors

Norwalk virus (NV) is the prototype strain of human noroviruses (HuNoVs), a group of positive-strand RNA viruses in the Caliciviridae family and the leading cause of epidemic gastroenteritis worldwide. Investigation of HuNoV replication and development of antiviral therapeutics in cell culture remai...

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Bibliographische Detailangaben
Hauptverfasser: Qu, Lin, Vongpunsawad, Sompong, Atmar, Robert L., Prasad, B. V. Venkataram, Estes, Mary K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178847/
https://ncbi.nlm.nih.gov/pubmed/25008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01111-14
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