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Characterization of the Termini of Cytoplasmic Hepatitis B Virus Deproteinated Relaxed Circular DNA

The biosynthesis of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) requires the removal of the covalently linked viral polymerase from the 5′ end of the minus strand [(−)strand] of viral relaxed circular DNA (rcDNA), which generates a deproteinated rcDNA (DP-rcDNA) intermediate. In...

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Publicado en:J Virol
Autores principales: Cai, Dawei, Yan, Ran, Xu, Jerry Z., Zhang, Hu, Shen, Sheng, Mitra, Bidisha, Marchetti, Alexander, Kim, Elena S., Guo, Haitao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737736/
https://ncbi.nlm.nih.gov/pubmed/33055252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00922-20
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