Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases

BACKGROUND: In vivo assessment of neuroinflammation by 18-kDa translocator protein positron-emission-tomography (TSPO-PET) ligands receives growing interest in preclinical and clinical research of neurodegenerative disorders. Higher TSPO-PET binding as a surrogate for microglial activation in female...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Biechele, Gloria, Franzmeier, Nicolai, Blume, Tanja, Ewers, Michael, Luque, Jose Medina, Eckenweber, Florian, Sacher, Christian, Beyer, Leonie, Ruch-Rubinstein, Francois, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Cumming, Paul, Bartenstein, Peter, Rominger, Axel, Höglinger, Günter U., Herms, Jochen, Brendel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737385/
https://ncbi.nlm.nih.gov/pubmed/33317543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02046-2
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