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Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania

Myeloproliferative neoplasms are characterized by mutations in JAK2, MPL and CALR genes. Commonly in diagnostics and previous studies mainly sequencing and common PCR techniques under conventional detection limits are used. Splanchnic vein thromboses are rare, but often appear associated with myelop...

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書目詳細資料
發表在:	Biomark Res
Main Authors:	Grunwald, Luise, Grosse-Thie, Christina, Sender, Sina, Knuebel, Gudrun, Krohn, Saskia, Roolf, Catrin, Junghanss, Christian, Henze, Larissa, Murua Escobar, Hugo
格式:	Artigo
語言:	Inglês
出版:	BioMed Central 2020
主題:	Letter to the Editor
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7737343/ https://ncbi.nlm.nih.gov/pubmed/33317584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-020-00254-9
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Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania

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