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In vivo characterization of toxicity of norcocaethylene and norcocaine identified as the most toxic cocaine metabolites in male mice

BACKGROUND: Majority of cocaine users also consume alcohol, and concurrent use of cocaine and alcohol produces cocaethylene, norcocaine, norcocaethylene, and other non-toxic metabolites. It is essential to know their relative toxicity for development of a truly effective therapeutics for cocaine tox...

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Zheng, Xirong, Shang, Linyue, Zhan, Chang-Guo, Zheng, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737241/
https://ncbi.nlm.nih.gov/pubmed/31499241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2019.04.033
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