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Screening for functional transcriptional and splicing regulatory variants with GenIE
Genome-wide association studies (GWAS) have identified numerous genetic loci underlying human diseases, but a fundamental challenge remains to accurately identify the underlying causal genes and variants. Here, we describe an arrayed CRISPR screening method, Genome engineering-based Interrogation of...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736817/ https://ncbi.nlm.nih.gov/pubmed/33152068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa960 |
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